Details for gene set INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch
Phenotype	phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch
Upregulated in class	truncNotch
GeneSet	INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)
Enrichment Score (ES)	0.71287256
Normalized Enrichment Score (NES)	1.4268351
Nominal p-value	0.06946983
FDR q-value	0.5489998
FWER p-Value	1.0

Fig 1: Enrichment plot: INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RGS10	2340292	711	2.399	0.2931	Yes
2	RGS14	380086	2062	1.165	0.3814	Yes
3	RGS3	60670 540736 1340180 1500369 3390735 4010131 4610402 6380114	2154	1.101	0.5286	Yes
4	RGS19	7050427	2268	1.037	0.6657	Yes
5	RGS6	6040601	3029	0.637	0.7129	Yes
6	RGS9	1050273	6831	0.084	0.5201	No
7	GNAQ	430670 4210131 5900736	7189	0.072	0.5108	No
8	RGS18	1780019	7774	0.055	0.4871	No
9	RGS7	3390044	9319	0.023	0.4072	No
10	RGS11	2360041	9763	0.015	0.3855	No
11	RGS16	780091	11349	-0.011	0.3018	No
12	RGS4	2970711	12660	-0.041	0.2370	No
13	RGS17	1400603	12780	-0.044	0.2367	No
14	RGS13	3780722	13336	-0.063	0.2157	No
15	RGS1	4060347 4540181	13477	-0.069	0.2177	No
16	RGS2	1090736	14637	-0.182	0.1805	No
17	RGS20	4540541 4730086	14926	-0.242	0.1984	No

Fig 3: INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING): Random ES distribution
Gene set null distribution of ES for INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)